Author

L. Funkhouser-Jones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

L. D. Sibley· 3 shared R. Xu· 2 shared A. Kimball· 1 shared D. A. Schaefer· 1 shared E. A. Kennedy· 1 shared G. Wilke· 1 shared H. Makimaa· 1 shared K. Ackerman· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMicrobiology

L. D. Sibley

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3 papers

Recent·Most cited

Mendelian segregation and high recombination rates facilitate genetic analyses in Cryptosporidium parvum

A. Kimball, L. Funkhouser-Jones, W. Huang, R. Xu, W. H. Witola, L. D. Sibley

This study investigates meiotic processes in Cryptosporidium parvum by analyzing chromosome segregation and recombination rates using transgenic parasites and in vitro cultures, revealing Mendelian inheritance and high crossover rates.

bioRxiv · Feb 2, 2024 · PreprintMicrobiology

Microbiota produced indole metabolites disrupt host cell mitochondrial energy production and inhibit Cryptosporidium parvum growth

L. Funkhouser-Jones, R. Xu, G. Wilke, Y. Fu, L. A. Shriefer, H. Makimaa, R. Rodgers, E. A. Kennedy, K. VanDussen, T. Stappenbeck, M. T. Baldridge, L. D. Sibley

The paper identifies indole metabolites from the microbiota that inhibit Cryptosporidium parvum growth by disrupting host mitochondrial function and parasite mitosome membrane potential.

bioRxiv · May 25, 2023 · PreprintMicrobiology

Gut metabolites influence susceptibility of neonatal mice to cryptosporidiosis.

K. L. VanDussen, L. Funkhouser-Jones, M. E. Akey, D. A. Schaefer, K. Ackerman, M. W. Riggs, T. S. Stappenbeck, L. D. Sibley

This study identifies gut metabolites that influence susceptibility to Cryptosporidium infection in neonatal mice, showing that fatty acids affect parasite growth and invasion.

bioRxiv · Sep 11, 2020 · PreprintMicrobiology