Author

L. G. Rahme

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

V. K. SINGH· 2 shared A. A. Tzika· 1 shared A. Bandyopadhaya· 1 shared A. Chakraborty· 1 shared A. Felici· 1 shared C. Pignaffo· 1 shared D. Andreotti· 1 shared D. Maura· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

V. K. SINGH

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tackling Recalcitrant Pseudomonas aeruginosa Infections In Critical Illness via Anti-virulence Monotherapy

V. K. SINGH, M. Almpani, D. Maura, T. Kitao, L. Ferrari, S. Fontana, G. Bergamini, E. Calcaterra, C. Pignaffo, M. Negri, T. d. Oliveira Pereira, F. Skinner, M. Gkikas, D. Andreotti, A. Felici, , L. G. Rahme

This study identifies novel anti-MvfR compounds (NAMs) that reduce intestinal permeability and inflammation in Pseudomonas aeruginosa infections, offering a potential monotherapy for critical illness.

bioRxiv · Apr 27, 2022Microbiology

Immunometabolic hijacking of immune cells by a Pseudomonas aeruginosa quorum-sensing signal

A. Bandyopadhaya, V. K. Singh, A. Chakraborty, A. A. Tzika, L. G. Rahme

This study shows how Pseudomonas aeruginosa uses a quorum-sensing signal to reprogram macrophage metabolism, reducing energy and immune responses to promote pathogen persistence.

bioRxiv · Oct 3, 2021 · PreprintMicrobiology