Author

D. P. Bhatt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

D. Goldfarb· 2 shared K. M. LaPak· 2 shared M. B. Major· 2 shared M. D. Hirschey· 2 shared M. J. Agajanian· 2 shared O. R. Ilkayeva· 2 shared A. D. Axtman· 1 shared A. E. Adams· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

D. Goldfarb

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Protein proximity networks and functional evaluation of the Casein Kinase 1 γ family reveals unique roles for CK1γ3 in WNT signaling

M. J. Agajanian, F. M. Potjewyd, B. M. Bowman, S. Solomon, K. M. LaPak, D. P. Bhatt, J. L. Smith, D. Goldfarb, A. D. Axtman, M. B. Major

This study identifies unique roles for CK1γ3 in WNT signaling through proximity biotinylation, functional assays, and inhibitor testing, showing its distinct activation of β-catenin and Notch pathways.

bioRxiv · Nov 30, 2021Cell Biology

Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

M. Puray-Chavez, K. M. Lapak, T. P. Schrank, J. L. Elliott, D. P. Bhatt, M. J. Agajanian, R. Jasuja, D. Q. Lawson, K. Davis, P. W. Rothlauf, H. Jo, N. Lee, K. Tenneti, J. E. Eschbach, C. Shema Mugisha, , S. B. Kutluay

This study identifies H522 cells as ACE2-negative human cells permissive to SARS-CoV-2 infection, revealing alternative receptor usage and host response mechanisms.

bioRxiv · Mar 1, 2021Microbiology

Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans

J. P. Rooney, K. A. Hershberger, E. A. Turner, L. J. Donoghue, L. L. Maurer, I. T. Ryde, J. J. Kim, R. Joglekar, J. D. Hibshman, L. L. Smith, D. P. Bhatt, O. R. Ilkayeva, M. D. Hirschey, J. N. Meyer

This study shows that early-life mitochondrial DNA damage in C. elegans causes lifelong energy production deficits through redox signaling mechanisms.

bioRxiv · Nov 25, 2020Cell Biology

Deglutarylation of GCDH by SIRT5 controls lysine metabolism in mice

D. P. Bhatt, C. A. Mills, K. A. Anderson, B. J. Henriques, T. G. Lucas, S. Francisco, J. Liu, O. R. Ilkayeva, A. E. Adams, S. R. Kulkarni, D. S. Backos, P. A. Grimsrud, C. M. Gomes, M. D. Hirschey

This study identifies glutarylation of GCDH by glutaryl-CoA and shows SIRT5 deglutarylates GCDH, restoring its function and regulating lysine metabolism in mice.

bioRxiv · Jun 28, 2020 · PreprintBiochemistry