L. K. Cole

Tissue Specific Knockout of the Cardiolipin Transacylase Enzyme TAFAZZIN in Both Liver and Pancreatic Beta Cells Protects Mice From Diet-Induced Obesity

This study shows that knocking out tafazzin in both liver and pancreatic beta cells protects mice from diet-induced obesity by reducing weight gain and fat accumulation.

Altered Cardiolipin Metabolism is Associated with Cardiac Mitochondrial Dysfunction in Pulmonary Vascular Remodeled Perinatal Rat Pups

This study examines phospholipid metabolism in perinatal rat pups with pulmonary vascular remodeling, finding altered cardiolipin and phosphatidylethanolamine levels linked to mitochondrial dysfunction and cardiac dysfunction.

Tafazzin deficiency in mouse mesenchymal stem cells potentiates their immunosuppression and impairs activated B lymphocyte immune function

This study shows that Tafazzin deficiency in mouse mesenchymal stem cells enhances their immunosuppressive effects on activated B lymphocytes.

Tafazzin regulates the function of lipopolysaccharide activated B lymphocytes in mice

This study shows that tafazzin deficiency impairs B cell function and metabolism in response to lipopolysaccharide in mice.

The Cardiolipin Transacylase Tafazzin Regulates Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets from Mice

This study shows that Tafazzin deficiency in pancreatic islets reduces insulin secretion and mitochondrial function under low-glucose conditions.

Berberine alleviates adiposity and cardiac dysfunction in offspring exposed to gestational diabetes mellitus

This study shows that berberine treatment reduces adiposity and improves cardiac and pancreatic function in offspring exposed to gestational diabetes mellitus.