L. Lin

The paper uses QTL mapping to show MHC variants bias TRBV gene usage in UCB samples, revealing germline-encoded TCR-MHC contacts influence TCR repertoire.

PIRD is a database that collects and stores annotated TCR and BCR sequencing data, along with tools for visualization and analysis.

The paper identifies Bayogenin 3-O-Cellobioside as a novel anti-blast metabolite in rice, showing a correlation with blast resistance across different cultivars.

The paper identifies NbP3IP as a plant protein that induces autophagy and degrades RSV p3, inhibiting viral infection.

The paper identifies PDHK1 as a synthetic-essential gene in PTEN-deficient cells and cancers, showing its upregulation drives aerobic glycolysis and correlates with poor patient survival.

This study analyzes TCRB and IGH repertoires in IgAN patients to identify non-invasive biomarkers for diagnosis.

This study identifies novel germline V and J alleles in Rhesus macaques by analyzing BCR repertoires and validates them using whole genome sequencing and alignment reference.

The paper develops a mathematical model of the Hippo pathway in Drosophila to explain growth and patterning, showing how changes in pathway inputs affect tissue size and shape.

This paper develops a computational framework to predict dynamic polytherapy switching strategies to address tumor heterogeneity and evolution in lung adenocarcinoma.