Author

L. Ndhlovu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. J. Corley· 2 shared A. Di Narzo· 1 shared A. Gala· 1 shared A. Kasarskis· 1 shared A. Levescot· 1 shared A. Livanos· 1 shared A. P. Pang· 1 shared A. Stojmirovic· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

M. J. Corley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states

L. Ndhlovu, M. Bendall, V. B. Dwaraka, A. P. Pang, N. Dopkins, N. Carreras, R. Smith, D. Nixon, M. J. Corley

This study constructs epigenetic clocks using retroelement DNA methylation states to predict chronological age across human tissues and species, showing their reversibility and responsiveness to HIV treatment.

bioRxiv · Dec 6, 2023 · PreprintImmunology

Human Galectin-9 Potently Enhances SARS-CoV-2 Replication and Inflammation in Airway Epithelial Cells

L. Du, M. S. Bouzidi, A. Gala, F. Deiter, J.-N. Billaud, S. Yeung, P. Dabral, J. Jin, G. Simmons, Z. Dossani, T. Niki, L. Ndhlovu, J. Greenland, S. K. Pillai

This study shows that galectin-9 enhances SARS-CoV-2 replication and inflammation in airway epithelial cells by promoting viral entry and activating pro-inflammatory pathways.

bioRxiv · Mar 18, 2022Microbiology

Disruption of natural killer cell homing as a biomarker in persons aging with or without HIV

K. W. Kroll, S. V. Shah, O. Lucar, T. A. Premeaux, C. M. Shikuma, M. Corley, M. Mosher, S. Bowler, L. Ndhlovu, R. K. Reeves

The paper analyzes NK cell phenotypic changes with aging in HIV-infected and uninfected individuals, finding altered trafficking markers in HIV that correlate with aging.

bioRxiv · Jan 5, 2022 · PreprintImmunology

Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease

M. Suarez-Farinas, M. Tokuyama, G. Wei, R. Huang, A. Livanos, D. Jha, A. Levescot, H. Irizar, R. Kosoy, S. Cording, W. Wang, H. Irizar, R. Ungaro, A. Di Narzo, G. Martinez-Delgado, , S. Mehandru

The paper examines how intestinal inflammation affects ACE2 and TMPRSS2 expression and identifies shared molecular networks between COVID-19 and IBD.

bioRxiv · May 21, 2020Immunology