Author

M. J. Corley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

L. C. Ndhlovu· 3 shared H. M. Ko· 2 shared J.-F. Colombel· 2 shared L. Ndhlovu· 2 shared M. Tokuyama· 2 shared S. Mehandru· 2 shared A. Chokola· 1 shared A. Di Narzo· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

L. C. Ndhlovu

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5 papers

Recent·Most cited

Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states

L. Ndhlovu, M. Bendall, V. B. Dwaraka, A. P. Pang, N. Dopkins, N. Carreras, R. Smith, D. Nixon, M. J. Corley

This study constructs epigenetic clocks using retroelement DNA methylation states to predict chronological age across human tissues and species, showing their reversibility and responsiveness to HIV treatment.

bioRxiv · Dec 6, 2023 · PreprintImmunology

Multiplex analysis of cytokines and chemokines in persons aging with or without HIV

K. W. Kroll, G. Woolley, K. Terry, T. A. Premeaux, C. M. Shikuma, M. J. Corley, S. Bowler, L. C. Ndhlovu, R. K. Reeves

This study uses multiplex analysis to examine cytokines and chemokines in aging HIV-positive and healthy individuals, finding age and treatment-related variations in plasma biomarkers.

bioRxiv · Jan 30, 2023Immunology

Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease

M. Suarez-Farinas, M. Tokuyama, G. Wei, R. Huang, A. Livanos, D. Jha, A. Levescot, H. Irizar, R. Kosoy, S. Cording, W. Wang, H. Irizar, R. Ungaro, A. Di Narzo, G. Martinez-Delgado, , S. Mehandru

The paper examines how intestinal inflammation affects ACE2 and TMPRSS2 expression and identifies shared molecular networks between COVID-19 and IBD.

bioRxiv · May 21, 2020Immunology

Comparative in vitro transcriptomic analyses of COVID-19 candidate therapy hydroxychloroquine suggest limited immunomodulatory evidence of SARS-CoV-2 host response genes.

M. J. Corley, C. Sugai, M. Schotsaert, R. E. Schwartz, L. C. Ndhlovu

This study examines HCQ's transcriptomic effects in vitro and finds limited overlap with SARS-CoV-2 host response genes, suggesting limited immunomodulatory evidence for HCQ in COVID-19.

bioRxiv · Apr 13, 2020 · PreprintImmunology

Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1 infected individuals

M. Uzzan, M. Tokuyama, A. K. Rosenstein, C. Tomescu, I. N. SahBandar, H. M. Ko, L. Leyre, A. Chokola, E. Kaplan-Lewis, G. Rodriguez, A. Seki, M. J. Corley, J. Aberg, A. La Porte, E.-y. Park, , S. Mehandru

Anti-α4β7 therapy reduces lymphoid aggregates in the gastrointestinal tract of HIV-1 infected individuals with mild inflammatory bowel disease.

bioRxiv · Jun 14, 2018Immunology