Author

R. K. Reeves

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Assay:flow cytometry· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:rat· 2

Frequent Co-Authors

K. Kroll· 3 shared C. M. Shikuma· 2 shared C. Manickam· 2 shared G. Woolley· 2 shared K. W. Kroll· 2 shared M. Mosher· 2 shared O. Lucar· 2 shared R. Jones· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

K. Kroll

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6 papers

Recent·Most cited

Multiplex analysis of cytokines and chemokines in persons aging with or without HIV

K. W. Kroll, G. Woolley, K. Terry, T. A. Premeaux, C. M. Shikuma, M. J. Corley, S. Bowler, L. C. Ndhlovu, R. K. Reeves

This study uses multiplex analysis to examine cytokines and chemokines in aging HIV-positive and healthy individuals, finding age and treatment-related variations in plasma biomarkers.

bioRxiv · Jan 30, 2023Immunology

Disruption of natural killer cell homing as a biomarker in persons aging with or without HIV

K. W. Kroll, S. V. Shah, O. Lucar, T. A. Premeaux, C. M. Shikuma, M. Corley, M. Mosher, S. Bowler, L. Ndhlovu, R. K. Reeves

The paper analyzes NK cell phenotypic changes with aging in HIV-infected and uninfected individuals, finding altered trafficking markers in HIV that correlate with aging.

bioRxiv · Jan 5, 2022 · PreprintImmunology

A Novel CRISPR-Engineered, Stem Cell-Derived Cellular Vaccine

K. Chakraborty, A. Chandrashekar, A. Sidaway, E. Latta, J. Yu, K. McMahan, C. Manickam, K. Kroll, M. Mosher, R. K. Reeves, R. Gam, E. Arthofer, M. Choudhry, D. H. Barouch, T. Henley

This paper describes a CRISPR-engineered cellular vaccine designed to mimic natural immunity, showing robust neutralizing antibody responses and reduced viral load in non-human primates.

bioRxiv · Dec 28, 2021 · PreprintImmunology

Systemic and mucosal mobilization of granulocyte subsets during lentivirus infection

R. Jones, C. Manickam, D. R. Ram, K. Kroll, B. Hueber, G. Woolley, S. V. Shah, S. Smith, V. Varner, R. K. Reeves

This study examines granulocyte subset dynamics in systemic and mucosal tissues during lentivirus infection in rhesus macaques, finding altered frequencies in chronic infection, particularly in gastrointestinal mucosae.

bioRxiv · Mar 19, 2021Immunology

Probiotic Supplementation Reduces Inflammatory Profiles But Does Not Prevent Oral Immune Perturbations During SIV Infection

R. K. Reeves

This study evaluates the effects of oral probiotic supplementation on SIV infection in rhesus macaques, finding reduced inflammation but no prevention of oral immune perturbations.

bioRxiv · Dec 17, 2020Immunology

Human antigen-specific memory natural killer cell responses develop against HIV-1 and influenza virus and are dependent on MHC-E restriction

S. Jost, O. Lucar, T. Yoder, K. Kroll, S. Sugawara, S. Smith, R. Jones, G. Tweet, A. Werner, P. J. Tomezsko, H. L. Dugan, J. Ghofrani, M. Altfeld, A. Grundhoff, M. Muller-Trutwin, , R. K. Reeves

This study shows human NK cells develop antigen-specific memory against HIV-1 and influenza via MHC-E restriction, validated through single-cell cloning and biomarker analysis.

bioRxiv · Nov 9, 2020 · PreprintImmunology