Author

L. P. Deleyrolle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

G. Tian· 3 shared C. Yang· 2 shared D. A. Mitchell· 2 shared J. Huang· 2 shared J. K. Harrison· 2 shared M. Sarkisian· 2 shared A. Chakraborty· 1 shared A. Doty· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

G. Tian

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4 papers

Recent·Most cited

KR158 spheres harboring slow-cycling cells recapitulate GBM features in an immunocompetent system

A. Chakraborty, C. Yang, J. L. Kresak, A. Silver, D. Feier, G. Tian, M. Andrews, O. O. Sobanjo, O. O. Sobanjo, E. D. Hodge, M. K. Engelbart, J. Huang, J. K. Harrison, M. Sarkisian, D. A. Mitchell, L. P. Deleyrolle

This study validates a murine model of glioblastoma stem cells that recapitulate human features and enables investigation of their interactions with the immune system.

bioRxiv · Jan 26, 2024 · PreprintCancer Biology

Aurora Kinase A Inhibition plus Tumor Treating Fields Suppress Glioma Cell Proliferation in a Cilium-Independent Manner

J. Tian, J. Mallinger, P. Shi, D. Ling, L. P. Deleyrolle, M. Lin, H. Khoshbouei, M. Sarkisian

This paper shows that combining Aurora Kinase A inhibition with Tumor Treating Fields reduces glioma cell proliferation, and this effect is not dependent on cilia.

bioRxiv · Nov 29, 2023Cancer Biology

Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+ myeloid cells into the tumor microenvironment in a redundant manner

G. P. Takacs, C. J. Kreiger, D. Luo, G. Tian, J. S. Garcia, L. P. Deleyrolle, D. A. Mitchell, J. K. Harrison

This study shows that CCL2 and CCL7 from gliomas redundantly recruit CCR2+/CX3CR1+ myeloid cells into the tumor microenvironment, contributing to immune suppression and poor prognosis in GBM.

bioRxiv · Jul 8, 2022Cancer Biology

Slow-cycling cells in glioblastoma: a specific population in the cellular mosaic of cancer stem cells

C. Yang, G. Tian, M. Dajac, A. Doty, S. Wang, J.-H. Lee, M. Rahman, J. Huang, B. A. Reynolds, M. R. Sarkisian, D. Mitchell, L. P. Deleyrolle

This study compares slow-cycling cells with cancer stem cell (CSC)-like cells in glioblastoma, showing phenotypic and functional heterogeneity and supporting the cancer stem cell mosaicism model.

bioRxiv · Jan 25, 2022Cancer Biology