Author

J. S. Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Animal Behavior & Cognition· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Organism:mouse· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

E. S. Winer· 2 shared G. P. Takacs· 2 shared J. K. Harrison· 2 shared M. R. Luskin· 2 shared R. M. Stone· 2 shared A. Apffel· 1 shared A. Mullally· 1 shared A. Sherman· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

E. S. Winer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Floral Cues and Flower Handling Tactics Affect Switching Decisions by Nectar-Foraging Bumble Bees

M. Baek, J. S. Garcia, D. R. Papaj

This study shows that bumble bees prefer to switch flower colors while keeping their handling tactics, but switch tactics when colors are very different and they have experience with legitimate visitation.

bioRxiv · May 1, 2024Animal Behavior & Cognition

Systemically targeting monocytic MDSCs using dendrimers and their cell-level biodistribution kinetics

C. A. Littrell, G. P. Takacs, C. Siva Sankara, A. Sherman, K. A. Rubach, J. S. Garcia, C. Bell, J. K. Harrison, F. Zhang

This study examines how hydroxyl dendrimers are taken up by M-MDSCs in tumor and lymphoid organs, showing differential uptake based on dendrimer functionality and serum proteins.

bioRxiv · Feb 14, 2024 · PreprintBioengineering

Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+ myeloid cells into the tumor microenvironment in a redundant manner

G. P. Takacs, C. J. Kreiger, D. Luo, G. Tian, J. S. Garcia, L. P. Deleyrolle, D. A. Mitchell, J. K. Harrison

This study shows that CCL2 and CCL7 from gliomas redundantly recruit CCR2+/CX3CR1+ myeloid cells into the tumor microenvironment, contributing to immune suppression and poor prognosis in GBM.

bioRxiv · Jul 8, 2022Cancer Biology

BCOR and BCORL1 mutations disrupt PRC1.1 repressive function in leukemia by unlinking the RING-PCGF1 enzymatic core from target genes

E. J. Schaefer, W. C. Wang, C. A. Meyer, P. Cejas, M. D. Gearhart, E. R. Adelman, I. Fares, A. Apffel, K. Lim, Y. Xie, C. J. Gibson, M. Schenone, H. M. Murdock, E. S. Wang, L. P. Gondek, , R. C. Lindsley

This study shows BCOR and BCORL1 mutations disrupt PRC1.1 function in leukemia by separating its enzymatic core from chromatin targets, leading to treatment resistance.

bioRxiv · Mar 8, 2021 · PreprintCancer Biology

Reconstructing the lineage histories and differentiation trajectories of individual cancer cells in JAK2-mutant myeloproliferative neoplasms

D. Van Egeren, J. Escabi, M. Nguyen, S. Liu, C. R. Reilly, S. Patel, B. Kamaz, M. Kalyva, D. J. DeAngelo, I. Galinsky, M. Wadleigh, E. S. Winer, M. R. Luskin, R. M. Stone, J. S. Garcia, , S. Hormoz

This study reconstructs the lineage histories and differentiation trajectories of JAK2-mutant HSCs in MPN patients, finding the mutation occurs decades before diagnosis and drives exponential growth of mutated HSC populations.

bioRxiv · Aug 24, 2020Cancer Biology