Author

L. Palomero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2

Frequent Co-Authors

M. A. Pujana· 3 shared A. E. Casey· 2 shared H. Kim· 2 shared M. Mahendralingam· 2 shared R. Khokha· 2 shared A. Aytes· 1 shared A. Font· 1 shared A. Indacochea· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

M. A. Pujana

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Author profile →

4 papers

Recent·Most cited

Mammary lineage dictates homologous recombination repair and PARP inhibitor vulnerability

H. Kim, A. E. Casey, L. Palomero, M. Mahendralingam, M. Parsons, S. Narala, F. Mateo, S. Hofer, P. D. Waterhouse, T. Kislinger, M. A. Pujana, H. K. Berman, R. Khokha

The paper shows that mammary epithelial lineage determines HR and PARP inhibitor vulnerability, with luminal cells having high-fidelity HR and PARPi sensitivity.

bioRxiv · May 14, 2021 · PreprintCancer Biology

Taxane induces attenuation of the CXCR2/BCL-2 axis and sensitize prostate cancer to platinum-based treatments

V. Ruiz de Porras, X. C. Wang, L. Palomero, M. Marin-Aguilera, A. Indacochea, N. Jimenez, B. Mellado, S. Bystrup, C. Sole-Blanch, J. M. Piulats, J. F. Suarez, J. C. Pardo, E. Martinez-Balibrea, A. Aytes, A. Font

This paper identifies that taxane treatment reduces CXCR2 and BCL-2 in mCRPC, making tumors more sensitive to platinum-based therapies.

bioRxiv · Jan 20, 2020 · PreprintCancer Biology

Mammary epithelial cells have lineage-restricted metabolic identities

M. Mahendralingam, K. Aliar, A. E. Casey, D. Pellacani, H. Kim, V. Ignatchenko, M. G. Valero, L. Palomero, A. Sinha, V. Stambolic, M. Alam, A. Schimmer, H. Berman, M. A. Pujana, C. J. Eaves, , R. Khokha

The paper identifies lineage-restricted metabolic identities in normal mammary epithelial cells and links them to breast cancer metabolic heterogeneity.

bioRxiv · Oct 8, 2019Cell Biology

Subjugation of TGFβ Signaling by Human Papilloma Virus in Head and Neck Squamous Cell Carcinoma Shifts DNA Repair from Homologous Recombination to Alternative End-Joining

Q. Liu, L. Ma, T. Jones, L. Palomero, M. A. Pujana, H. Martinez-Ruiz, P. Ha, J. Murnane, I. Cuartas, J. Seoane, M. Baumann, A. Linge, M. H. Barcellos-Hoff

This study shows HPV-positive HNSCC cells lose TGFβ signaling, shifting DNA repair from homologous recombination to alternative end-joining, increasing PARP inhibitor sensitivity.

Clinical Cancer Research · Dec 3, 2018Peer-reviewedCancer Biology