Author

T. Kislinger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

R. Khokha· 4 shared B. Zhang· 2 shared C. W. McCloskey· 2 shared H. K. Berman· 2 shared M. Govindarajan· 2 shared M. Waas· 2 shared P. Tharmapalan· 2 shared S. Narala· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersCancer Biology

R. Khokha

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

FABP7 Progenitors are a Targetable Metabolic Root in the BRCA1 Breast

C. W. McCloskey, B. Zhang, M. Waas, G. Abazari, F. Vyas, K. Aliar, P. Tharmapalan, A. Kuttanamkuzhi, S. Narala, J. Cruikshank, S. O. P. Hofer, H. W. Jackson, T. Kislinger, H. K. Berman, R. Khokha

This study identifies FABP7 progenitors as a targetable metabolic root in BRCA1 breast cancer, showing their dysregulation and potential inhibition via fatty acid metabolism disruption.

bioRxiv · Nov 2, 2023 · PreprintCell Biology

Droplet based low input proteomic platform for rare cell populations

M. Waas, A. Khoo, P. Tharmapalan, C. W. McCloskey, M. Govindarajan, B. Zhang, S. Khan, P. Waterhouse, R. Khokha, T. Kislinger

DROPPS enables high-fidelity proteomic profiling of rare cell populations with low input, revealing CD36 as a marker of progenitor capacity in mammary basal cells.

bioRxiv · Sep 11, 2023 · PreprintBiochemistry

Glycoproteomics Identifies Plexin-B3 as Targetable Cell Surface Protein Required for Growth and Invasion of Triple Negative Breast Cancer Cells

L. Kuhlmann, M. Govindarajan, S. Mejia-Guerrero, V. Ignatchenko, L. Y. Liu, B. T. Grunwald, J. Cruickshank, H. Berman, R. Khokha, T. Kislinger

This study identifies Plexin-B3 as a cell surface protein essential for TNBC growth and invasion, using glycoproteomics and functional validation.

bioRxiv · Jun 1, 2022 · PreprintCancer Biology

Mammary lineage dictates homologous recombination repair and PARP inhibitor vulnerability

H. Kim, A. E. Casey, L. Palomero, M. Mahendralingam, M. Parsons, S. Narala, F. Mateo, S. Hofer, P. D. Waterhouse, T. Kislinger, M. A. Pujana, H. K. Berman, R. Khokha

The paper shows that mammary epithelial lineage determines HR and PARP inhibitor vulnerability, with luminal cells having high-fidelity HR and PARPi sensitivity.

bioRxiv · May 14, 2021 · PreprintCancer Biology