Author

L. Pazzaglia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

K. Scotlandi· 2 shared A. C. De Luca· 1 shared A. Di Giannatale· 1 shared C. Blanco· 1 shared C. P. Theuer· 1 shared C. Romagosa Perez-Portabella· 1 shared C. Savini· 1 shared D. J. Pisapia· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

K. Scotlandi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis

T. Gonzalez-Munoz, A. Di Giannatale, S. Garcia-Silva, V. Santos, S. Sanchez-Redondo, C. Savini, O. Grana-Castro, C. Blanco, D. J. Pisapia, J. L. Peralto, C. Romagosa Perez-Portabella, R. Alaggio, M. S. Benassi, L. Pazzaglia, K. Scotlandi, , H. Peinado

This study identifies endoglin (ENG) as a biomarker and therapeutic target for MPNSTs, showing that targeting ENG with antibodies or combining it with MEK inhibitors reduces tumor growth and metastasis.

Clinical Cancer Research · Jul 11, 2023Peer-reviewedCancer Biology

Profilin 1 deficiency drives mitotic defects and impairs genome stability

F. Scotto di Carlo, S. Russo, F. Muyas, M. Mangini, L. Pazzaglia, F. Biamonte, A. C. De Luca, K. Scotlandi, I. Cortes-Ciriano, F. Gianfrancesco

This study shows that Profilin 1 deficiency causes mitotic defects and genome instability in cancer cells.

bioRxiv · Feb 1, 2022Cell Biology