Author

L. R. Pelgrom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Zawistowska-Deniziak· 3 shared B. Guigas· 3 shared J. M. Lambooij· 3 shared M. Yazdanbakhsh· 3 shared A. Ozir-Fazalalikhan· 2 shared B. Everts· 2 shared F. Otto· 2 shared H. J. P. van der Zande· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. Zawistowska-Deniziak

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3 papers

Recent·Most cited

LKB1 signalling in dendritic cells controls whole-body metabolic homeostasis by limiting T helper 17 priming

H. J. P. van der Zande, E. C. Brombacher, J. M. Lambooij, L. R. Pelgrom, A. Zawistowska-Deniziak, T. A. Patente, G. A. Heieis, F. Otto, A. Ozir-Fazalalikhan, M. Yazdanbakhsh, B. Everts, B. Guigas

This study shows that LKB1 in dendritic cells limits T helper 17 cell priming, thereby protecting against obesity-induced metabolic dysfunctions.

bioRxiv · Oct 14, 2021 · PreprintImmunology

Soluble mannose receptor induces pro-inflammatory macrophage activation and metaflammation

M. Embgenbroich, H. J. van der Zande, L. Hussaarts, J. Schulte-Schrepping, L. R. Pelgrom, N. Garcia-Tardon, L. Schlautmann, I. Stoetzel, K. Handler, J. M. Lambooij, A. Zawistowska-Deniziak, L. Hoving, K. de Ruiter, M. Wijngaarden, H. Pijl, , S. Burgdorf

This study shows that soluble mannose receptor (sMR) promotes pro-inflammatory macrophage activation and metaflammation by inhibiting CD45 phosphatase activity, leading to metabolic dysfunctions in obesity.

bioRxiv · Sep 29, 2020 · PreprintImmunology

The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type-2 immunity-independent inhibition of food intake

H. J. P. van der Zande, M. A. Gonzalez, K. de Ruiter, R. Wilbers, N. Garcia-Tardon, M. van Huizen, K. van Noort, L. R. Pelgrom, J. M. Lambooij, A. Zawistowska-Deniziak, F. Otto, A. Ozir-Fazalalikhan, D. van Willigen, M. Welling, J. Poles, , B. Guigas

This paper shows that the helminth glycoprotein omega-1 improves metabolic health in obese mice by reducing food intake, independent of type 2 immunity.

bioRxiv · Jul 3, 2020Immunology