Author

T. A. Patente

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:flow cytometry· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

B. Everts· 3 shared B. Guigas· 3 shared A. Zawistowska-Deniziak· 2 shared E. C. Brombacher· 2 shared F. Otto· 2 shared G. A. Heieis· 2 shared J. M. Lambooij· 2 shared A. H. de Ru· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

B. Everts

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

AMPK activation induces RALDHhigh tolerogenic dendritic cells through rewiring of glucose and lipid metabolism

E. C. Brombacher, T. A. Patente, A. J. van der Ham, T. J. A. Moll, F. Otto, F. W. M. Verheijen, E. A. Zaal, A. H. de Ru, R. T. N. Tjokrodirijo, C. R. Berkers, P. A. van Veelen, B. Guigas, B. Everts

This study shows that AMPK activation makes human dendritic cells more tolerogenic by altering their metabolism, specifically increasing RALDH activity and changing lipid and glucose metabolism.

bioRxiv · Jul 4, 2023 · PreprintImmunology

Spectral flow cytometry reveals metabolic heterogeneity in tissue macrophages

G. A. Heieis, T. A. Patente, T. Tak, L. Almeida, B. Everts

This study uses spectral flow cytometry to reveal metabolic heterogeneity in tissue macrophages across different organs and under infection conditions.

bioRxiv · May 26, 2022Immunology

Fasciola hepatica Fatty Acid Binding Protein 1 modulates T cell polarization by promoting dendritic cell thrombospondin-1 secretion without affecting metabolic homeostasis in obese mice

A. Zawistowska-Deniziak, J. M. Lambooij, T. A. Patente, M. Lapinski, H. J. van der Zande, K. Basalaj, C. de Korne, M. A. Chaye, T. Gasan, L. J. Norbury, M. Giera, A. Zaldumbide, H. H. Smits, B. Guigas

bioRxiv · Apr 1, 2022Immunology

LKB1 signalling in dendritic cells controls whole-body metabolic homeostasis by limiting T helper 17 priming

H. J. P. van der Zande, E. C. Brombacher, J. M. Lambooij, L. R. Pelgrom, A. Zawistowska-Deniziak, T. A. Patente, G. A. Heieis, F. Otto, A. Ozir-Fazalalikhan, M. Yazdanbakhsh, B. Everts, B. Guigas

This study shows that LKB1 in dendritic cells limits T helper 17 cell priming, thereby protecting against obesity-induced metabolic dysfunctions.

bioRxiv · Oct 14, 2021 · PreprintImmunology