LKB1 signalling in dendritic cells controls whole-body metabolic homeostasis by limiting T helper 17 priming
H. J. P. van der Zande, E. C. Brombacher, J. M. Lambooij, L. R. Pelgrom, A. Zawistowska-Deniziak, T. A. Patente, G. A. Heieis, F. Otto, A. Ozir-Fazalalikhan, M. Yazdanbakhsh, B. Everts, B. Guigas
This study shows that LKB1 in dendritic cells limits T helper 17 cell priming, thereby protecting against obesity-induced metabolic dysfunctions.
bioRxiv · Oct 14, 2021 · PreprintImmunology