Author

G. A. Heieis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:flow cytometry· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

B. Everts· 3 shared G. Perona-Wright· 2 shared R. M. Maizels· 2 shared T. A. Patente· 2 shared A. L. Shergold· 1 shared A. Ozir-Fazalalikhan· 1 shared A. T. Andrusaite· 1 shared A. Zawistowska-Deniziak· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

B. Everts

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A PD-1-ST2 axis controls Th2 effector function in tissue via a metabolic checkpoint

G. A. Heieis, B. Everts, C. W. Roberts, R. M. Maizels, G. Perona-Wright

This study shows that PD-1 signaling regulates Th2 cell metabolism and IL-33 receptor expression through fatty acid oxidation, suggesting PD-1 blockade could treat Th2-related diseases.

bioRxiv · Aug 13, 2023 · PreprintImmunology

Spectral flow cytometry reveals metabolic heterogeneity in tissue macrophages

G. A. Heieis, T. A. Patente, T. Tak, L. Almeida, B. Everts

This study uses spectral flow cytometry to reveal metabolic heterogeneity in tissue macrophages across different organs and under infection conditions.

bioRxiv · May 26, 2022Immunology

LKB1 signalling in dendritic cells controls whole-body metabolic homeostasis by limiting T helper 17 priming

H. J. P. van der Zande, E. C. Brombacher, J. M. Lambooij, L. R. Pelgrom, A. Zawistowska-Deniziak, T. A. Patente, G. A. Heieis, F. Otto, A. Ozir-Fazalalikhan, M. Yazdanbakhsh, B. Everts, B. Guigas

This study shows that LKB1 in dendritic cells limits T helper 17 cell priming, thereby protecting against obesity-induced metabolic dysfunctions.

bioRxiv · Oct 14, 2021 · PreprintImmunology

Tissue-based IL-10 signalling in helminth infection limits IFNγ expression and promotes the intestinal Th2 response

H. C. Webster, V. Gamino, A. L. Shergold, A. T. Andrusaite, G. A. Heieis, S. W. F. Milling, R. M. Maizels, G. Perona-Wright

This study shows IL-10 promotes Th2 responses and suppresses IFNγ in intestinal helminth infection by regulating Th1 cells.

bioRxiv · Aug 10, 2021Immunology