Author

L. Radnai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:imaging· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

C. A. Miller· 3 shared G. Rumbaugh· 3 shared T. M. Kamenecka· 3 shared E. J. Young· 2 shared L. Lin· 2 shared P. Griffin· 2 shared R. F. Stremel· 2 shared A. Dovas· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

C. A. Miller

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Author profile →

3 papers

Recent·Most cited

MT-125 Inhibits Non-Muscle Myosin IIA and IIB, Synergizes with Oncogenic Kinase Inhibitors, and Prolongs Survival in Glioblastoma

R. Kenchappa, L. Radnai, E. J. Young, N. Zarco, L. Lin, A. Dovas, C. T. Meyer, A. Haddock, A. Hall, P. T. Canoll, M. Cameron, N. K. Nagaiah, G. Rumbaugh, P. R. Griffin, T. M. Kamenecka, , S. S. Rosenfeld

bioRxiv · Apr 27, 2024 · PreprintCancer Biology

Discovery of a Novel, Selective and Short-Acting Skeletal Myosin II Inhibitor

L. Radnai, M. Surman, M. Hafenbreidel, E. J. Young, R. F. Stremel, L. Lin, P. Pasetto, X. Jin, M. Geedy, J.-R. Partridge, A. Patel, M. Conlon, J. R. Sellers, M. D. Cameron, G. Rumbaugh, , C. A. Miller

This study discovers and characterizes skeletostatins, selective skeletal myosin II inhibitors with improved properties for research and drug development.

bioRxiv · Jul 28, 2020 · PreprintPharmacology & Toxicology

A Simple and Robust Cell Based Assay for the Discovery of Novel Cytokinesis Inhibitors

L. Radnai, R. F. Stremel, T. Vaissiere, W. H. Martin, G. Rumbaugh, T. M. Kamenecka, P. Griffin, C. A. Miller

This paper develops a cell-based assay to identify cytokinesis inhibitors, showing reliable EC50 values and good separation between positive and negative controls.

bioRxiv · Jan 9, 2020Cell Biology