Author

T. M. Kamenecka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:imaging· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

C. A. Miller· 2 shared G. Rumbaugh· 2 shared L. Radnai· 2 shared P. Griffin· 2 shared R. F. Stremel· 2 shared A. Patel· 1 shared C. Doebelin· 1 shared E. J. Young· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. A. Miller

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Author profile →

3 papers

Recent·Most cited

Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement.

T. S. Strutzenberg, S. J. Novick, R. D. Garcia-Ordonez, C. Doebelin, Y. He, M. R. Chang, T. M. Kamenecka, P. R. Griffin

This study investigates conformational changes in RORγ during DNA recognition and coregulator engagement using structural proteomics and small angle X-ray scattering.

bioRxiv · May 25, 2021Biophysics

Discovery of a Novel, Selective and Short-Acting Skeletal Myosin II Inhibitor

L. Radnai, M. Surman, M. Hafenbreidel, E. J. Young, R. F. Stremel, L. Lin, P. Pasetto, X. Jin, M. Geedy, J.-R. Partridge, A. Patel, M. Conlon, J. R. Sellers, M. D. Cameron, G. Rumbaugh, , C. A. Miller

This study discovers and characterizes skeletostatins, selective skeletal myosin II inhibitors with improved properties for research and drug development.

bioRxiv · Jul 28, 2020 · PreprintPharmacology & Toxicology

A Simple and Robust Cell Based Assay for the Discovery of Novel Cytokinesis Inhibitors

L. Radnai, R. F. Stremel, T. Vaissiere, W. H. Martin, G. Rumbaugh, T. M. Kamenecka, P. Griffin, C. A. Miller

This paper develops a cell-based assay to identify cytokinesis inhibitors, showing reliable EC50 values and good separation between positive and negative controls.

bioRxiv · Jan 9, 2020Cell Biology