Author

L.-Y. Hsu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. T. Rosenbaum· 2 shared R. A. Miller· 2 shared A. Cauvet· 1 shared A. Weiss· 1 shared C. M. Hill· 1 shared D. Chang· 1 shared D. Li· 1 shared D. Rychkov· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

J. T. Rosenbaum

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Author profile →

3 papers

Recent·Most cited

Soquelitinb, A selective inhibitor of interleukin-2-inducible kinase (ITK), is active in several murine models of T cell-mediated inflammatory disease

L.-Y. Hsu, J. T. Rosenbaum, S. Lindner, Y. Allanore, A. Cauvet, R. D. Pawar, D. Li, M. Van Den Brink, R. A. Miller

This study shows that soquelitinib inhibits ITK and reduces T cell-mediated inflammation in multiple murine models.

bioRxiv · Oct 27, 2023 · PreprintImmunology

Selective inhibition of interleukin-2 inducible T cell kinase (ITK) enhances anti-tumor immunity in association with Th1-skewing, cytotoxic T cell activation, and reduced T cell exhaustion

L.-Y. Hsu, J. T. Rosenbaum, E. Verner, W. B. Jones, C. M. Hill, J. W. Janc, J. J. Buggy, N. Ding, J. C. Reneau, M. S. Khodadoust, Y. H. Kim, R. A. Wilcox, R. A. Miller

bioRxiv · Jul 5, 2023 · PreprintCancer Biology

Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis

J. Ashouri, L.-Y. Hsu, S. Yu, D. Rychkov, Y. Chen, D. Chang, M. Sirota, E. Hansen, L. Lattanza, J. Zikherman, A. Weiss

The paper identifies arthritogenic CD4 T cells in murine and human autoimmune arthritis using Nur77 as a marker of TCR signaling.

bioRxiv · Mar 12, 2019Immunology