Author

J. T. Rosenbaum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

L. Karstens· 2 shared L.-Y. Hsu· 2 shared M. Asquith· 2 shared R. A. Miller· 2 shared S. Diamond· 2 shared T. M. Martin· 2 shared A. Cauvet· 1 shared C. M. Hill· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

L. Karstens

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Soquelitinb, A selective inhibitor of interleukin-2-inducible kinase (ITK), is active in several murine models of T cell-mediated inflammatory disease

L.-Y. Hsu, J. T. Rosenbaum, S. Lindner, Y. Allanore, A. Cauvet, R. D. Pawar, D. Li, M. Van Den Brink, R. A. Miller

This study shows that soquelitinib inhibits ITK and reduces T cell-mediated inflammation in multiple murine models.

bioRxiv · Oct 27, 2023 · PreprintImmunology

Selective inhibition of interleukin-2 inducible T cell kinase (ITK) enhances anti-tumor immunity in association with Th1-skewing, cytotoxic T cell activation, and reduced T cell exhaustion

L.-Y. Hsu, J. T. Rosenbaum, E. Verner, W. B. Jones, C. M. Hill, J. W. Janc, J. J. Buggy, N. Ding, J. C. Reneau, M. S. Khodadoust, Y. H. Kim, R. A. Wilcox, R. A. Miller

bioRxiv · Jul 5, 2023 · PreprintCancer Biology

Axial spondyloarthritis patients have altered mucosal IgA response to oral and fecal microbiota

T. Gill, P. Stauffer, M. Asquith, T. Laderas, T. M. Martin, S. Davin, M. Schleisman, C. Ramirez, K. Ogle, I. Lindquist, J. Nguyen, S. R. Planck, C. Shaut, S. Diamond, J. T. Rosenbaum, L. Karstens

This study finds altered IgA responses to gut and oral microbiota in axial spondyloarthritis patients using IgA-SEQ and metagenomic analysis.

bioRxiv · Jul 15, 2021Immunology

HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome

M. Asquith, P. R. Sternes, M.-E. Costello, L. Karstens, S. Diamond, T. M. Martin, T. D. Spector, K.-A. le Cao, J. T. Rosenbaum, M. A. Brown

This study identifies HLA-B27 and HLA-DRB1 alleles associated with altered gut microbiome composition in healthy individuals, suggesting a role for these alleles in influencing microbiome dynamics linked to ankylosing spondylitis and rheumatoid arthritis.

bioRxiv · Mar 5, 2019Microbiology