Xenotransplanted human cortical neurons reveal species-specific development and functional integration into mouse visual circuits.
Daniele Linaro, Ben Vermaercke, Ryohei Iwata, Arjun Ramaswamy, Baptiste Libé‐Philippot, Leïla Boubakar, Brittany A. Davis, Keimpe D. B. Wierda, Kristofer Davie, Suresh Kumar Poovathingal, Pier-Andrée Penttilä, Angéline Bilheu, Lore De Bruyne, David Gall, Karl‐Klaus Conzelmann, , Pierre Vanderhaeghen
This study transplants human cortical neurons into mice to study their development and integration into mouse visual circuits, finding prolonged juvenile features and functional synaptic integration.
Neuron · Nov 21, 2019Peer-reviewedNeuroscience