Author

Lorelai Pop

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adityanarayanan RadhakrishnaniD· 1 shared Alexander MeissneriD· 1 shared Duncan M. MorganiD· 1 shared Emi A. LutziD· 1 shared Eric S. LanderiD· 1 shared Fiona ChatterjeeiD· 1 shared Jain Yajit· 1 shared John Christopher LoveiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adityanarayanan RadhakrishnanORCID

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1 paper

Recent·Most cited

PD-1 blockade during T cell priming enhances long-term protection against metastatic tumors by epigenetically tuning T cell exhaustion

Teresa Dinter, Sebastian D. Mackowiak, Zachary J. Rogers, Vidit Bhandarkar, Molly Y. Carney, Yiming J. Zhang, Duncan M. Morgan, Lorelai Pop, Fiona Chatterjee, Emi A. Lutz, Jain Yajit, Adityanarayanan Radhakrishnan, Eric S. Lander, Karl Dane Wittrup, John Christopher Love, , Stefani Spranger

This study shows PD-1 blockade during T cell priming promotes an intermediate-exhausted CD8 T cell state that supports durable anti-tumor immunity after surgery and metastatic challenge, better than effector or memory-like T cells.

bioRxiv · Nov 25, 2025 · PreprintImmunology