Author

Loretta Viera Preval

University of Nevada, Las Vegas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

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Research Focus:chromatin & epigenetic regulation· 3 Assay:proteomics· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Henning Jacob JesseniD· 3 shared Kevin RitteriD· 3 shared Nguyen Tran· 3 shared Prasun GuhaiD· 3 shared Zachary SiniD· 3 shared Anas K. Gremida· 2 shared Anuj Shukla· 2 shared George Koshkaryan· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

Henning Jacob JessenORCID

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Author profile →

3 papers

Recent·Most cited

Fasting disrupts the InsP6 HDAC3 axis to drive ER stress-mediated clearance of DNA-damaged cells and enforce tissue quality control.

Sujan Chetterjee, Zachary Sin, Richard Van, Nguyen Tran, Tam Tran, Anuj Shukla, Lucile M. Jeusset, George Koshkaryan, Kevin Saldana, Rayan Muneer, Loretta Viera Preval, Lingkun Gu, Faizan Bhat, Kevin Ritter, Katherine Huang, , Prasun Guha

The paper shows that fasting disrupts the TGF-β-InsP6-HDAC3 axis, inducing ER stress and eliminating DNA-damaged cells to maintain tissue quality.

bioRxiv · May 27, 2026 · PreprintCell Biology

Phytic Acid (InsP6) Activates HDAC3 Epigenetic Axis to Maintain Intestinal Barrier Function

Sujan Chatterjee, Zachary Sin, Nguyen Tran, Loretta Viera Preval, Anuj Shukla, Tam Tran, George Koshkaryan, Kevin Ritter, Xue Bessie Su, Saharat Jolak Ragsac, Seungman Park, Qian Liu, Richard Van, Katherine Huang, Kayci Huff-Hardy, , Prasun Guha

The paper shows that phytic acid activates the HDAC3 epigenetic axis to maintain intestinal barrier function, with therapeutic potential in inflammatory bowel disease.

Nature Communications · Feb 9, 2026Peer-reviewedCell Biology

βA3/A1-crystallin is an epigenetic regulator of histone deacetylase 3 (HDAC3) in the retinal pigmented epithelial (RPE) cells

Sujan Chatterjee, Sayan Ghosh, Zachary Sin, Vishnu Suresh Babu, Loretta Viera Preval, Emily Davis, Nguyen Tran, Sridhar Bammidi, Pooja Gautam, Stacey Hose, Yuri V. Sergeev, Miguel Flores‐Bellver, Kevin Ritter, Henning Jacob Jessen, Issam Aldiri, , Prasun Guha

The paper identifies βA3/A1-crystallin as an epigenetic regulator of HDAC3 in RPE cells, showing it enhances HDAC3 activity through CK2 interaction and InsP6 regulation, linking it to AMD pathogenesis.

Aging Cell · Jul 15, 2025Peer-reviewedCell Biology