Phytic Acid (InsP6) Activates HDAC3 Epigenetic Axis to Maintain Intestinal Barrier Function
Sujan Chatterjee, Zachary Sin, Nguyen Tran, Loretta Viera Preval, Anuj Shukla, Tam Tran, George Koshkaryan, Kevin Ritter, Xue Bessie Su, Saharat Jolak Ragsac, Seungman Park, Qian Liu, Richard Van, Katherine Huang, Kayci Huff-Hardy, , Prasun Guha
The paper shows that phytic acid activates the HDAC3 epigenetic axis to maintain intestinal barrier function, with therapeutic potential in inflammatory bowel disease.
Nature Communications · Feb 9, 2026Peer-reviewedCell Biology