Author

Lucas E. Wittenborn

University of Illinois Urbana-Champaign

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Akshita Baiju GopaliD· 2 shared Arjun Mehta· 2 shared Chris Ka Pun MokiD· 2 shared Emily X. Ma· 2 shared Huibin LviD· 2 shared Jessica J. Huang· 2 shared Madison R. ArdaghiD· 2 shared Mateusz SzlembarskiiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Akshita Baiju GopalORCID

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2 papers

Recent·Most cited

Structure basis for distinct protective mechanisms of IGHV3-23 antibodies targeting influenza hemagglutinin stem

Huibin Lv, Yang Wei Huan, Tossapol Pholcharee, Qi Wen Teo, Wenkan Liu, Akshita Baiju Gopal, Danbi Choi, Madison R. Ardagh, Timothy J.C. Tan, Yuanxin Sun, Arjun Mehta, Jinghang Li, Mateusz Szlembarski, Jessica J. Huang, Emily X. Ma, , Nicholas C. Wu

This study identifies three IGHV3-23 antibodies targeting influenza HA stem, showing that non-neutralizing antibodies with enhanced Fc-mediated effector functions offer better in vivo protection than a potent neutralizer.

bioRxiv · Nov 6, 2025 · PreprintImmunology

Evolution of antibody cross-reactivity to influenza H5N1 neuraminidase from an N2-specific germline

Huibin Lv, Yang Wei Huan, Qi Wen Teo, Chunke Chen, Tossapol Pholcharee, Akshita Baiju Gopal, Madison R. Ardagh, Jessica J. Huang, Ruipeng Lei, Xin Chen, Yuanxin Sun, Yun Sang Tang, Arjun Mehta, Mateusz Szlembarski, Kevin J. Mao, , Nicholas C. Wu

This study identifies an antibody that cross-reacts with H5N1 and H3N2 neuraminidases and shows how somatic hypermutation enables this cross-reactivity.

Cell Host & Microbe · Oct 18, 2025Peer-reviewedImmunology