Author

Danbi Choi

University of Illinois Urbana-Champaign

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Huibin LviD· 4 shared Nicholas C. WuiD· 4 shared Akshita Baiju GopaliD· 3 shared Qi Wen TeoiD· 3 shared Timothy J.C. TaniD· 3 shared Chris Ka Pun MokiD· 2 shared Madison R. ArdaghiD· 2 shared Tossapol PholchareeiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Huibin LvORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Somatic evolution of a cross-reactive germline antibody that expands its breadth to neutralize new SARS-CoV-2 variants

Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita Baiju Gopal, Danbi Choi, Timothy J.C. Tan, Yun Sang Tang, Lewis Yu-Lam Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris Ka Pun Mok

This study identifies a cross-reactive germline antibody that can be evolved to neutralize multiple SARS-CoV-2 variants through targeted somatic mutations.

bioRxiv · Mar 25, 2026 · PreprintImmunology

Structure basis for distinct protective mechanisms of IGHV3-23 antibodies targeting influenza hemagglutinin stem

Huibin Lv, Yang Wei Huan, Tossapol Pholcharee, Qi Wen Teo, Wenkan Liu, Akshita Baiju Gopal, Danbi Choi, Madison R. Ardagh, Timothy J.C. Tan, Yuanxin Sun, Arjun Mehta, Jinghang Li, Mateusz Szlembarski, Jessica J. Huang, Emily X. Ma, , Nicholas C. Wu

This study identifies three IGHV3-23 antibodies targeting influenza HA stem, showing that non-neutralizing antibodies with enhanced Fc-mediated effector functions offer better in vivo protection than a potent neutralizer.

bioRxiv · Nov 6, 2025 · PreprintImmunology

High-throughput synthesis and specificity characterization of natively paired antibodies using oPool+ display

Wenhao O. Ouyang, Huibin Lv, Wenkan Liu, Ruipeng Lei, Zongjun Mou, Tossapol Pholcharee, Logan Talmage, Meixuan Tong, Wei Ji, Yiquan Wang, Katrine E. Dailey, Akshita Baiju Gopal, Danbi Choi, Madison R. Ardagh, Lucia A. Rodriguez, , Nicholas C. Wu

This study introduces oPool+ display, a high-throughput platform for synthesizing and characterizing natively paired antibodies, demonstrating its application in analyzing influenza HA antibodies.

Science Translational Medicine · Sep 3, 2025Peer-reviewedImmunology

Deep mutational scanning of influenza A virus NEP reveals pleiotropic mutations in its N-terminal domain

Qi Wen Teo, Yiquan Wang, Huibin Lv, Kevin J. Mao, Timothy J.C. Tan, Yang Wei Huan, Joel Rivera-Cardona, Evan K. Shao, Danbi Choi, Zahra Tavakoli Dargani, Christopher B. Brooke, Nicholas C. Wu

This study uses deep mutational scanning to analyze the functional impact of NEP mutations in influenza A virus, revealing pleiotropic effects on viral replication and host adaptation.

bioRxiv · May 16, 2024 · PreprintCell Biology