Emily H. Thomas

Early intervention with a PACAP lactoside following repetitive mild traumatic brain injury prevents persistent LHb hyperactivity and motivational deficits in male mice

This study shows that early administration of a PACAP agonist prevents mTBI-induced LHb hyperactivity and motivational deficits in mice, while late administration has limited efficacy and potential side effects.

Neuroanatomical and behavioral characterization of corticotropin releasing factor-expressing lateral Habenula neurons in mice

This study identifies a novel population of CRF-expressing lateral habenula neurons in mice and characterizes their sex-specific behavioral and electrophysiological properties.

Effects of Repetitive Mild Traumatic Brain Injury on Corticotropin-Releasing Factor Modulation of Lateral Habenula Excitability and Motivated Behavior

This study investigates how repetitive mild traumatic brain injury (mTBI) affects corticotropin-releasing factor (CRF) modulation of lateral habenula (LHb) excitability and motivated behavior in male and female mice, revealing sex-specific neurobehavioral effects.

Dysregulation of Kappa Opioid Receptor Neuromodulation of Lateral Habenula Synaptic Function following a Repetitive Mild Traumatic Brain Injury

This study investigates how repetitive mild traumatic brain injury (mTBI) affects Kappa Opioid Receptor (KOR) neuromodulation of lateral habenula (LHb) synaptic function in male and female mice, revealing changes in excitatory/inhibitory balance.

AKAP150-anchored PKA regulation of synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the lateral habenula

This study investigates the role of AKAP150 in regulating synaptic transmission, plasticity, and CRF neuromodulation in the lateral habenula using genetic and electrophysiological approaches.