Insulin-Like Growth Factor 1 Receptor Regulates Breast Cancer Cell Adhesion through Beta-1 Integrin
Christopher A Galifi, Elvan Dogan, Luis Fernandez Almansa, Krystopher Maingrette, Simran S. Shah, Joseph J. Bulatowicz, Karen Ebenezer, Utz Herbig, Amir Kamal Miri, Teresa L. Wood
This study shows that IGF1R regulates breast cancer cell adhesion through β1 integrin, with both IGF-1 stimulation and IGF1R knockdown increasing adhesion by removing IGF1R from the cell surface.
Frontiers in Endocrinology · May 20, 2026Peer-reviewedCancer Biology