Christopher Varsanyi

This study shows that Cdc50, a lipid flippase regulatory subunit in Cryptococcus neoformans, controls membrane lipid homeostasis, extracellular vesicle biogenesis, and macrophage interactions, with loss of Cdc50 increasing phagocytosis and susceptibility to macrophage killing.

This study shows that Xkr8 and TMEM16F regulate distinct PS externalization mechanisms in the tumor microenvironment, influencing immune evasion and tumor growth.

This paper develops PS-targeting chimeric IFN fusion proteins that enhance anti-tumor activities by combining IFN-β and IFN-λ with the PS-binding Gas6 domain.