Author

Lukas Wagner

Charité – Universitätsmedizin Berlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adriano B Chaves-Filho· 1 shared Alexander Astashyn· 1 shared Alina M. WinkelkotteiD· 1 shared Almut SchulzeiD· 1 shared Anderas Schneeweiss· 1 shared Angela RiedeliD· 1 shared Beate MayeriD· 1 shared Bernhard Kuester· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

Adriano B Chaves-Filho

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3 papers

Recent·Most cited

Catabolism of extracellular glutathione is a driver of metastasis formation

Felix C. E. Vogel, Florian Roehrig, Danny Schilling, Adriano B Chaves-Filho, Greta Mattavelli, Maximilian Kraemer, Julie Haenlin, Alina M. Winkelkotte, Valentine Fournier, Kamal M. Al-Shami, H. Rohdjeß, Philipp Poeller, Tanja Poth, Christoph Stange, Bernhard Kuester, , Almut Schulze

The paper identifies extracellular glutathione catabolism as a driver of metastasis by enabling proliferation and oxidative stress resistance in metabolically challenging microenvironments.

bioRxiv · Oct 13, 2026 · PreprintCancer Biology

Resolving RH and GYP hybrid alleles while accessing the entire blood group genome with Nanopore adaptive sampling

Morgan Gueuning, Gian Andri Thun, Samuel Koller, S. Sigurdardottir, N. Trost, Lukas Wagner, Beate Mayer, Charlotte Engström, Maja P. Mattle‐Greminger, S. Meyer

This study evaluates adaptive sampling for resolving complex blood group variants using long-read sequencing, identifying novel alleles and hybrid haplotypes in RH and MNS systems.

medRxiv · Jun 10, 2025 · PreprintGenetic & Genomic Medicine

Rapid and sensitive detection of genome contamination at scale with FCS-GX

Alexander Astashyn, Eric S. Tvedte, Deacon Sweeney, Victor Sapojnikov, Nathan Bouk, Victor Joukov, Eyal Mozes, Pooja K Strope, Pape M. Sylla, Lukas Wagner, Shelby L. Bidwell, Larissa C. Brown, Karen Clark, Emily W. Davis, Brian J. Smith-White, , Terence D. Murphy

FCS-GX, a hashed k-mer cross-species aligner with a 709 Gbp curated database, screens most genomes in 0.1-10 minutes and flagged 36.8 Gbp of contamination in GenBank.

Genome biology · Feb 26, 2024Peer-reviewedBioinformatics✦ In-depth digest