Author

Luying Pei

Novartis (Switzerland)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Organism:human· 1 Organism:plant (other)· 1

Frequent Co-Authors

Armand Guiguemde· 2 shared Steffen RenneriD· 2 shared Alexander Theodore Chao· 1 shared Amr Hamed Mahmoud· 1 shared Anke Harupa-ChungiD· 1 shared Armin PasseckeriD· 1 shared Basil T. ThommeniD· 1 shared Bin FangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Armand Guiguemde

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A high-throughput compound screen identifies multiple druggable targets in Plasmodium falciparum transmission stages

Leonie Seefeldt, Christin Gumpp, Olivia Carril, Jérôme Eberhardt, Sylwia D. Boltryk, Armin Passecker, Basil T. Thommen, Kleopatra Sifoniou, Christian Scheurer, Christoph Fischli, Deszoe Imre Babai, Amr Hamed Mahmoud, Leila T. Alexander, Steffen Renner, Armand Guiguemde, , Nicolas M. B. Brancucci

This study identifies three druggable targets in Plasmodium falciparum gametocytes using high-throughput screening and reveals resistance mechanisms for one compound.

bioRxiv · Sep 13, 2026 · PreprintMolecular Biology

Screening of a chemogenetic library unveils dual-stage antimalarials with low cytotoxicity

Laura Torres, Matthew E. Fishbaugher, Melanie Lam, Alexander Theodore Chao, Calla Martyn, Luying Pei, Debapriya Sengupta, Maxime Dauphinais, Jonathan E. Gable, Srinivasa P. S. Rao, Steffen Renner, Armand Guiguemde, Sebastian A. Mikolajczak, Anke Harupa-Chung, Gabriel Mitchell

This study screens a chemogenetic library to identify antimalarial compounds with dual-stage activity against Plasmodium liver and blood stages, showing low cytotoxicity.

bioRxiv · Oct 26, 2025 · PreprintMicrobiology

Compound activity prediction with dose-dependent transcriptomic profiles and deep learning

William J. Godinez, Vladimir Trifonov, Bin Fang, Guray Kuzu, Luying Pei, W. Armand Guiguemde, Éric Martin, Frederick J. King, Jeremy L. Jenkins, Peter Skewes-Cox

The paper introduces TAT models to predict compound activity using dose-dependent transcriptomic profiles, achieving 51% assay prediction success and validating malaria inhibitor identification.

Journal of Chemical Information and Modeling · Jan 31, 2024Peer-reviewedBioinformatics