Author

M. A. Child

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. J. Wincott· 3 shared E. Alves· 3 shared H. J. Benns· 3 shared A. Fairweather· 1 shared C. Dominicus· 1 shared C. Gilabert-Carbajo· 1 shared C. Tiengwe· 1 shared E. M. Frickel· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

C. J. Wincott

Mutual co-authors in cluster

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3 papers

Recent·Most cited

An extracellular redox signal triggers calcium release and impacts the asexual development of Toxoplasma gondii

E. Alves, H. J. Benns, L. Magnus, C. Dominicus, T. Dobai, J. Blight, C. J. Wincott, M. A. Child

This study shows that extracellular redox signals trigger calcium release in Toxoplasma gondii, affecting its asexual development and egress.

bioRxiv · Feb 4, 2021Microbiology

Prioritization of antimicrobial targets by CRISPR-based oligo recombineering

H. J. Benns, M. Storch, J. Falco, F. R. Fisher, E. Alves, C. J. Wincott, J. Baum, G. S. Baldwin, E. Weerapana, E. W. Tate, M. A. Child

This paper introduces CORe, a CRISPR-based method to prioritize reactive amino acids for drug discovery by linking sequence reactivity to protein function in Toxoplasma gondii.

bioRxiv · Feb 4, 2021Microbiology

Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization

C. J. Wincott, G. Sritharan, H. J. Benns, F. B. Liakath, C. Gilabert-Carbajo, M. Bunyan, A. Fairweather, E. Alves, I. Andrews, L. Game, E. M. Frickel, C. Tiengwe, S. E. Ewald, M. A. Child

The paper develops a CRISPR-based barcoding method for protozoa and applies it to Toxoplasma gondii, showing the blood-brain barrier is not a major bottleneck for colonization.

bioRxiv · Aug 6, 2020Microbiology