M. A. Czekalska

This paper introduces smMDS, a method for digital sizing of proteins in solution, enabling sensitive and accurate measurement of protein sizes and interactions.

This study shows ANXA11 biomolecular condensates couple protein and lipid phase states on lysosomal membranes through interactions with ALG2 and CALC.

This study shows that alpha-synuclein oligomers bind more strongly to curved lipid membranes and displace monomeric alpha-synuclein, suggesting a new mechanism for Parkinson's disease toxicity.

The paper shows that proteins forming liquid condensates can reenter a phase-separated state at high salt concentrations due to hydrophobic and non-ionic interactions, distinct from low-salt electrostatic-driven phase separation.

This paper introduces a single-molecule microfluidic platform for digital protein biomarker detection, demonstrating its ability to quantify protein concentrations and provide insights beyond traditional immunoassays.