Author

M. A. Kukurugya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

B. D. Bennett· 2 shared N. Vu· 2 shared A. M. Westermark· 1 shared A. N. Lau· 1 shared C. H. Jan· 1 shared E. C. Lien· 1 shared F. McAllister· 1 shared J. E. Villalta· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPhysiology

B. D. Bennett

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2 papers

Recent·Most cited

Effects of aging on glucose and lipid metabolism in mice

E. C. Lien, N. Vu, A. M. Westermark, L. V. Danai, A. N. Lau, Y. Gultekin, M. A. Kukurugya, B. D. Bennett, M. Vander Heiden

This study examines how aging affects glucose and lipid metabolism in mice, finding that NAD+ levels remain stable but lipid metabolism increases in aged tissues.

bioRxiv · Dec 17, 2023Physiology

Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption

J. Yong, J. E. Villalta, N. Vu, M. A. Kukurugya, N. Olsson, M. P. Lopez, J. R. Lazzari-Dean, K. Hake, F. McAllister, B. D. Bennett, C. H. Jan

The paper identifies lipid homeostasis as a regulator of proteostasis, showing that lipid dysregulation disrupts ESCRT function and causes lysosomal protein aggregation.

bioRxiv · Nov 23, 2022 · PreprintCell Biology