Author

N. Olsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

J. E. Elias· 2 shared A. D. deSilva· 1 shared A. Lu· 1 shared A. Sette· 1 shared B. D. Bennett· 1 shared C. D. Marceau· 1 shared C. H. Jan· 1 shared D. Weiskopf· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

J. E. Elias

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption

J. Yong, J. E. Villalta, N. Vu, M. A. Kukurugya, N. Olsson, M. P. Lopez, J. R. Lazzari-Dean, K. Hake, F. McAllister, B. D. Bennett, C. H. Jan

The paper identifies lipid homeostasis as a regulator of proteostasis, showing that lipid dysregulation disrupts ESCRT function and causes lysosomal protein aggregation.

bioRxiv · Nov 23, 2022 · PreprintCell Biology

Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins

P. Saha, J. L. Shumate, J. G. Caldwell, N. Elghobashi-Meinhardt, A. Lu, L. Zhang, N. Olsson, J. E. Elias, S. R. Pfeffer

The paper investigates the role of inter-domain dynamics in cholesterol transport by NPC1 and NPC1L1 proteins, showing that domain movement is essential and that Ezetimibe inhibits NPC1L1 by binding to multiple domains.

bioRxiv · Mar 26, 2020Biochemistry

Immuno-proteomic interrogation of dengue infection reveals novel HLA haplotype-specific MHC-I antigens

K. Swaminathan, N. Olsson, P. J. Lund, C. D. Marceau, L. E. Wagar, Y. Tian, J. Sidney, D. Weiskopf, K. Majzoub, A. D. deSilva, E. Harris, M. M. Davis, A. Sette, J. E. Carette, J. E. Elias

This study identifies novel MHC-I antigens specific to dengue virus infection using an immuno-proteomics approach, revealing ligands associated with distinct HLA haplotypes and T-cell recognition.

bioRxiv · Nov 19, 2018 · PreprintImmunology