Author

M. C. B. Tan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

K. E. DelGiorno· 3 shared G. Wahl· 2 shared H. C. Maurer· 2 shared K. Lau· 2 shared N. Jyotsana· 2 shared N. K. Lytle· 2 shared O. Ben-Levy· 2 shared V. Q. Trinh· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersCancer Biology

K. E. DelGiorno

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3 papers

Recent·Most cited

Mutant GNAS drives a pyloric metaplasia with tumor suppressive glycans in intraductal papillary mucinous neoplasia

V. Q.-H. Trinh, K. E. Ankenbauer, S. M. Torbit, J. Liu, M. Batardiere, B. Kumar, H. C. Maurer, F. Revetta, Z. Chen, A. Kruse, A. Judd, C. Copeland, J. Wong, O. Ben-Levy, B. Jarvis, , K. E. DelGiorno

This study identifies GNASR201C as a driver of pyloric metaplasia in IPMN, characterized by tumor-suppressive glycans that inhibit cancer progression.

bioRxiv · Feb 25, 2024 · PreprintCancer Biology

Eicosanoids in the pancreatic tumor microenvironment: a multicellular, multifaceted progression

V. B. Gubbala, N. Jyotsana, V. Q. Trinh, H. C. Maurer, R. F. Naeem, N. K. Lytle, Z. Ma, S. Zhao, W. Lin, H. Han, Y. Shi, T. Hunter, P. K. singh, K. P. Olive, M. C. B. Tan, , K. E. DelGiorno

The paper identifies key eicosanoid changes in pancreatic tumorigenesis and the cell types responsible for their synthesis using mouse models and patient samples.

bioRxiv · Oct 27, 2021Cancer Biology

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury

Z. Ma, N. K. Lytle, B. Chen, N. Jyotsana, S. Weiser Novak, C. J. Cho, L. Caplan, O. Ben-Levy, A. C. Neininger, D. T. Burnette, V. Q. Trinh, M. C. B. Tan, E. A. Patterson, R. Arrojo e Drigo, R. R. Giraddi, , K. E. DelGiorno

The paper uses single-cell RNA sequencing to identify a conserved metaplasia program in pancreatic injury, revealing mucin/ductal populations and neoplastic transformation potential.

bioRxiv · Apr 9, 2021Cell Biology