Author

N. Jyotsana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Wahl· 2 shared K. E. DelGiorno· 2 shared M. C. B. Tan· 2 shared N. K. Lytle· 2 shared V. Q. Trinh· 2 shared Z. Ma· 2 shared A. C. Neininger· 1 shared A. L. Means· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

G. Wahl

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nanoparticle-mediated Targeting of the Fusion Gene RUNX1/ETO in t(8;21)-positive Acute Myeloid Leukaemia

H. Issa, L. Swart, M. Rasouli, M. Ashtiani, S. Nakjang, n. jyotsana, K. Schuschel, M. Heuser, H. Blair, O. Heidenreich

This study uses siRNA-loaded lipid nanoparticles to target the RUNX1/ETO fusion gene in t(8;21)-AML, showing improved survival and long-term inhibition of leukaemic growth.

bioRxiv · Sep 21, 2022Cancer Biology

Eicosanoids in the pancreatic tumor microenvironment: a multicellular, multifaceted progression

V. B. Gubbala, N. Jyotsana, V. Q. Trinh, H. C. Maurer, R. F. Naeem, N. K. Lytle, Z. Ma, S. Zhao, W. Lin, H. Han, Y. Shi, T. Hunter, P. K. singh, K. P. Olive, M. C. B. Tan, , K. E. DelGiorno

The paper identifies key eicosanoid changes in pancreatic tumorigenesis and the cell types responsible for their synthesis using mouse models and patient samples.

bioRxiv · Oct 27, 2021Cancer Biology

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury

Z. Ma, N. K. Lytle, B. Chen, N. Jyotsana, S. Weiser Novak, C. J. Cho, L. Caplan, O. Ben-Levy, A. C. Neininger, D. T. Burnette, V. Q. Trinh, M. C. B. Tan, E. A. Patterson, R. Arrojo e Drigo, R. R. Giraddi, , K. E. DelGiorno

The paper uses single-cell RNA sequencing to identify a conserved metaplasia program in pancreatic injury, revealing mucin/ductal populations and neoplastic transformation potential.

bioRxiv · Apr 9, 2021Cell Biology