Author

R. Arrojo e Drigo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:differential expression· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2

Frequent Co-Authors

A. Bautista· 2 shared J. E. Manning Fox· 2 shared J. Lyon· 2 shared P. E. MacDonald· 2 shared A. C. Neininger· 1 shared A. F. Spigelman· 1 shared A. L. Means· 1 shared A. Nie· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

A. Bautista

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 23, 2023

Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.

C. d. Santos, S. Shrestha, M. A. Cottam…·R. Arrojo e Drigo

This study shows caloric restriction enhances beta cell identity and homeostasis, delays aging and senescence, and improves mitochondrial function in pancreatic beta cells.

DOI 10.1101/2023.08.23.554369

mousescRNA-seq

𝕏 PostBluesky

Cell BiologybioRxivApr 9, 2021

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury

Z. Ma, N. K. Lytle, B. Chen…·K. E. DelGiorno

The paper uses single-cell RNA sequencing to identify a conserved metaplasia program in pancreatic injury, revealing mucin/ductal populations and neoplastic transformation potential.

DOI 10.1053/j.gastro.2021.10.027

mousescRNA-seq

𝕏 PostBluesky

Cell BiologybioRxivApr 8, 2021

Heterogenous impairment of α-cell function in type 2 diabetes is linked to cell maturation state

X.-Q. Dai, J. Camunas-Soler, L. J. Briant…·P. E. MacDonald

This study identifies heterogeneous α-cell dysfunction in type 2 diabetes linked to impaired maturation and electrophysiological changes.

DOI 10.1016/j.cmet.2021.12.021

humanmouse

𝕏 PostBluesky

PhysiologybioRxivPreprintAug 8, 2019

Aging of human endocrine pancreatic cell types is heterogeneous and sex-specific

R. Arrojo e Drigo, G. Erikson, S. Tyagi…·M. Hetzer

This study analyzes age-related changes in human endocrine pancreatic cell types, finding sex-specific and cell-type-specific effects of aging on beta cell function and transcriptional profiles.

DOI 10.1101/729541

humanscRNA-seq

𝕏 PostBluesky