D. T. Burnette

Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp

Resolution doubling in light-sheet microscopy via oblique plane structured illumination

This paper demonstrates isotropic resolution doubling in light-sheet microscopy using oblique plane structured illumination, achieving sub-150nm lateral resolution with reduced phototoxicity and faster volumetric imaging.

Mechanical counterbalance of kinesin and dynein motors in microtubular network regulates cell mechanics, 3D architecture, and mechanosensing

The paper shows dynein and kinesin motors balance microtubule network mechanics, affecting cell shape, adhesion, and mechanosensing through opposing actions on microtubule organization.

The Hippo pathway regulates density-dependent proliferation of iPSC-derived cardiac myocytes

This study shows that the Hippo pathway regulates density-dependent proliferation of iPSC-derived cardiac myocytes by modulating YAP/TAZ activity, with small molecules enhancing proliferation in low-density conditions.

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury

The paper uses single-cell RNA sequencing to identify a conserved metaplasia program in pancreatic injury, revealing mucin/ductal populations and neoplastic transformation potential.

MCL-1 inhibition by selective BH3 mimetics disrupts mitochondrial dynamics in iPSC-derived cardiomyocytes

This study shows that MCL-1 inhibition by BH3 mimetics disrupts mitochondrial dynamics and function in iPSC-derived cardiomyocytes, suggesting a non-apoptotic role for MCL-1 in cardiac health.

Precise tuning of cortical contractility regulates cell shape during cytokinesis

This study shows that balancing MII paralogs fine-tunes polar cortex tension to maintain cell shape during cytokinesis.