Rapid differentiation of regulatory CD4+ T cells in the infarcted myocardium blunts in situ inflammation
M. Delgobo, E. Weiss, D. E. Ashour, L. Popiolkowski, P. Arampatzi, V. Stangl, P. Arias-Loza, P. Rainer, A.-E. Saliba, B. Ludewig, U. Hofmann, S. Frantz, G. C. Ramos
This study shows that CD4+ T cells in the infarcted heart rapidly become regulatory, reducing inflammation, and identifies mechanisms of their differentiation and function.
bioRxiv · Mar 25, 2022Immunology