T. Dierckx

An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans

Serum GlycA level is a candidate biomarker for disease activity in systemic lupus erythematosus and for proliferative status of lupus nephritis, independent of renal function impairment.

This study shows Serum GlycA is elevated in systemic lupus erythematosus and correlates with disease activity and lupus nephritis, outperforming traditional biomarkers in predicting proliferative LN.

Age but not disease progression defines CD4+ and CD8+ T stem cell memory levels in human retroviral infections: contrasting effects of HTLV-1 and HIV-1

This study compares CD4+ and CD8+ TSCM levels in HTLV-1 and HIV-1 infections, finding age-driven accumulation in HTLV-1 and age-related loss in HIV-1 after treatment.

Decreased RORC expression and downstream signaling in HTLV-1-associated Adult T-cell Lymphoma/Leukemia uncovers an antiproliferative IL17 link: a potential target for immunotherapy?

The paper identifies decreased RORC expression and downstream antiproliferative IL17 signaling in ATL, suggesting therapeutic potential for boosting RORC/IL17 signaling.

ISG15 induces IL-10 production in human monocytes and is a biomarker of disease severity during active tuberculosis

The paper shows ISG15 induces IL-10 in human monocytes and correlates with TB disease severity.