Author

E. Weiss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5 Physiology· 2 Ecology· 1 Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Research Focus:host-pathogen & immune response· 6 Organism:mouse· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:metabolism & bioenergetics· 3 Research Focus:protein folding & dynamics· 3 Research Focus:cell signaling & trafficking· 2

Frequent Co-Authors

B. Parker· 4 shared A. Al-Yassin· 1 shared A. Chawla· 1 shared A. Graner· 1 shared A. I. Nesvizhskii· 1 shared A. Remenyi· 1 shared A. Stahl· 1 shared A. Statsyuk· 1 shared

Activity by Year

2016-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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4 shared papersBiochemistry

B. Parker

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Author profile →

11 papers

Recent·Most cited

LiF-MS+, a revised technique for mapping peptide-protein interactions

B. Parker, E. Weiss

LiF-MS+ improves peptide-protein interaction mapping by replacing the mass tag with a positively charged compound, enhancing detection of binding sites.

bioRxiv · May 28, 2024 · PreprintBiochemistry

Facile detection of peptide-protein interactions using an electrophoretic crosslinking shift assay

B. Parker, E. Weiss

The paper introduces ECSA, an electrophoretic crosslinking shift assay, to detect low-affinity peptide-protein interactions, demonstrating its effectiveness with MAP kinase and D-motif peptides.

bioRxiv · Apr 22, 2024Biochemistry

CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan

L. Heilg, F. Natasha, N. Trinks, V. K. AIMANIANDA BOPAIAH, S. Sze Wah Wong, T. Fontaine, U. Terpitz, L. Strobel, F. Le Mauff, D. Sheppard, S. Schaeuble, O. Kurzai, K. Huenniger, E. Weiss, M. Vargas, , J. Loeffler

This study identifies galactosaminogalactan as the fungal ligand for CD56 on human NK cells, triggering antifungal responses and immune cell activation.

bioRxiv · Aug 18, 2023 · PreprintMicrobiology

Unprecedented yet gradual nature of first millennium CE intercontinental crop plant dispersal revealed in ancient Negev desert refuse

D. Fuks, Y. Melamed, D. Langgut, T. Erickson-Gini, Y. Tepper, G. Bar-Oz, E. Weiss

The paper analyzes ancient Negev desert refuse to show that the first millennium CE was a significant period for crop dispersal, supporting a gradualist model over abrupt changes.

bioRxiv · Dec 1, 2022Ecology

Rapid differentiation of regulatory CD4+ T cells in the infarcted myocardium blunts in situ inflammation

M. Delgobo, E. Weiss, D. E. Ashour, L. Popiolkowski, P. Arampatzi, V. Stangl, P. Arias-Loza, P. Rainer, A.-E. Saliba, B. Ludewig, U. Hofmann, S. Frantz, G. C. Ramos

This study shows that CD4+ T cells in the infarcted heart rapidly become regulatory, reducing inflammation, and identifies mechanisms of their differentiation and function.

bioRxiv · Mar 25, 2022Immunology

Trade-Offs Between Hepatic Host Defense and Metabolic Programs Underlie Sex-Biased Diseases

J. Nikkanen, Y. A. Leong, W. C. Krause, D. Dermadi, J. A. Maschek, T. Van Ry, J. Cox, E. Weiss, O. Gokcumen, A. Chawla, H. Ingraham

This study identifies a sex-dependent trade-off between hepatic host defense and metabolic programs in mice, showing that BCL6 protects males from infection but increases metabolic disease risk under dietary excess.

bioRxiv · Jan 7, 2022Physiology

4 β-hydroxycholesterol is a pro-lipogenic factor that promotes SREBP1c expression and activity through Liver X-receptor.

O. Moldavski, P.-J. H. Zushin, C. A. Berdan, R. J. van Eijkeren, X. Jiang, M. Qian, D. S. Ory, D. F. Covey, D. Nomura, A. Stahl, E. Weiss, R. Zoncu

This study identifies 4β-hydroxycholesterol as a pro-lipogenic factor that activates SREBP1c via LXR to promote de novo lipogenesis.

bioRxiv · Aug 20, 2020Biochemistry

On the origin of photoperiod non-responsiveness in barley

R. Sharma, S. Shaaf, K. Neumann, Y. Guo, M. Mascher, M. David, A. Al-Yassin, H. Özkan, T. Blake, S. Hübner, N. P. Castaneda-Alvarez, S. Grando, S. Ceccarelli, M. Baum, A. Graner, , B. Kilian

This study identifies the origin of photoperiod non-responsiveness in barley by analyzing genetic variation and haplotype relationships in wild and domesticated barleys.

bioRxiv · Jul 2, 2020 · PreprintPlant Biology

Ndr/Lats kinases bind specific Mob-family coactivators through a conserved and modular interface

B. Parker, G. Gogl, M. Balint, C. Hetenyi, A. Remenyi, E. Weiss

The paper determines the crystal structures of Ndr/Lats kinase NTR-Mob complexes and identifies conserved residues involved in kinase-coactivator binding and activation.

bioRxiv · Mar 19, 2019Biochemistry

LiF-MS: Mapping unstructured peptide-protein interactions using Ligand-Footprinting Mass Spectrometry

B. Parker, E. Goncz, D. T. Krist, A. Statsyuk, A. I. Nesvizhskii, E. Weiss

This paper introduces LiF-MS, a method to map peptide-protein interactions by detecting binding sites and dynamic disorder using mass spectrometry.

bioRxiv · Jul 3, 2018 · PreprintBiochemistry

Adipocyte Jak2 Mediates Growth Hormone-Induced Hepatic Insulin Resistance

K. Corbit, J. P. G. Camporez, J. L. Tran, C. G. Wilson, D. Lowe, S. Nordstrom, K. Ganeshan, R. J. Perry, G. Schulman, M. J. Jurczak, E. Weiss

This study shows that adipocyte Jak2 mediates GH-induced hepatic insulin resistance through an adipose-dependent mechanism.

bioRxiv · Sep 20, 2016Physiology