Author

M. L. Shinohara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. E. Deerhake· 2 shared M. Inoue· 2 shared N. Aggarwal· 2 shared T. Nonaka· 2 shared W. E. Barclay· 2 shared A. Watwe· 1 shared B. A. Alman· 1 shared E. A. Miao· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

M. E. Deerhake

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3 papers

Recent·Most cited

AIM2 inflammasome activation in astrocytes occurs during the late phase of EAE

W. E. Barclay, M. E. Deerhake, M. Inoue, T. Nonaka, K. Nozaki, N. A. Luzum, N. Aggarwal, E. A. Miao, M. L. Shinohara

This study identifies AIM2 inflammasome activation in astrocytes during the late phase of EAE, distinct from traditional inflammasome-mediated inflammation.

bioRxiv · Oct 3, 2021 · PreprintImmunology

Dectin-1 limits central nervous system autoimmunity through a non-canonical pathway

M. E. Deerhake, K. Danzaki, M. Inoue, E. D. Cardakli, T. Nonaka, N. Aggarwal, W. E. Barclay, R. R. Ji, M. L. Shinohara

This study shows Dectin-1 protects against CNS autoimmunity through a non-canonical pathway independent of Card9, promoting neuroprotective molecules like Osm in myeloid cells and reducing EAE severity via astrocytic OsmR signaling.

bioRxiv · May 6, 2020 · PreprintImmunology

Yolk-Sac-Derived Macrophages Progressively Expand in the Mouse Kidney with Age

S. Ide, Y. Yahara, Y. Kobayashi, S. A. Strausser, A. Watwe, J. R. Pivratsky, S. D. Crowley, M. L. Shinohara, B. A. Alman, T. Souma

This study shows that yolk-sac-derived macrophages increase with age in the mouse kidney, becoming a major population in older mice.

bioRxiv · Oct 21, 2019Immunology