R. Rodriguez

A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma

This study identifies enasidenib as an effective treatment for IDH2 mutant chondrosarcoma through personalized medicine approaches involving sequencing, cell line models, and in vitro/in vivo testing.

Ether lipids influence cancer cell fate by modulating iron uptake

This study shows that ether lipids in cancer cells regulate membrane properties to influence iron uptake, ferroptosis, and metastasis, offering a therapeutic target.

Presence of Triatoma breyeri (Reduviidae, Triatominae) in Bolivia

The paper identifies Triatoma breyeri in Bolivia and suggests it was recently introduced through human activity, remaining confined to a specific dry valley region.

SMORES: A Simple Microfluidic Operating Room for the Examination and Surgery of Stentor coeruleus

SMORES is a microfluidic device that immobilizes Stentor coeruleus for microscopy and surgery with minimal disruption.

Host space, not energy or symbiont size, constrains feather mite abundance across passerine bird species

The paper investigates factors constraining feather mite abundance in passerine birds, finding host space rather than energy or symbiont size is the main constraint.

MarR-Dependent Transcriptional Regulation of mmpSL5 Induces Ethionamide Resistance in Mycobacterium abscessus

This study identifies MarR as a regulator of ethionamide resistance in Mycobacterium abscessus by showing that marR deletion increases resistance to ethionamide but not other antibiotics.

The evolution of two transmissible leukaemias colonizing the coasts of Europe

This study investigates the origin and evolution of two transmissible leukaemias in common cockles, identifying clonal origins, mutational signatures, and genomic instability.

Discovery of a druggable copper-signaling pathway that drives cell plasticity and inflammation

The paper identifies a copper-signaling pathway involving CD44 and mitochondrial copper(II) that drives inflammation and cell plasticity, and shows a metformin-based drug reduces inflammation in infection models.

Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) Up to 15 Months Post-Infection

This study finds SARS-CoV-2 S1 protein in non-classical monocytes in PASC patients up to 15 months post-infection, but not full-length viral RNA.

The dilemma of infection versus colonization at mucosal tissues: immunological and bacteriological features of obstructive tonsillar hypertrophy

This study investigates the role of immune cells and bacterial species in obstructive tonsillar hypertrophy, revealing their contribution to inflammation and epithelial barrier disruption.

VARIATIONS IN THE COVERAGE OF BIOLOGICAL SOIL CRUSTS ALONG A GRADIENT OF ARIDITY IN THE CENTER-WEST OF ARGENTINA

This study examines biocrust coverage and functional components across aridity gradients in Argentina, finding higher coverage in arid sites and significant differences among sites.

CD44 regulates epigenetic plasticity by mediating iron endocytosis

This study identifies CD44 as a mediator of iron endocytosis linked to epigenetic plasticity, showing iron's role in regulating histone modifications and gene expression during mesenchymal transitions.

Establishment of primary transgenic human airway epithelial cell cultures to study respiratory virus-host interactions

This study establishes a method to genetically modify primary human airway epithelial cells to study virus-host interactions without affecting innate immune responses or viral propagation.