Author

M. F. Jarrold

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1

Frequent Co-Authors

L. M. Miller· 2 shared A. J. Patterson· 1 shared A. Zlotnick· 1 shared B. Bothner· 1 shared B. E. Draper· 1 shared C. E. Catalano· 1 shared C. J. Schlicksup· 1 shared C. Kim· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

L. M. Miller

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages

T. N. Szyszka, M. P. Andreas, F. Lie, L. M. Miller, L. S. R. Adamson, F. Fatehi, R. Twarock, B. E. Draper, M. F. Jarrold, T. W. Giessen, Y. H. Lau

The paper shows that a single point mutation in a virus-like capsid can drive the formation of tetrahedral structures instead of the typical icosahedral symmetry.

bioRxiv · Feb 5, 2024Biochemistry

Biophysical and Structural Characterization of a Viral Genome Packaging Motor

N. S. Prokhorov, C. R. Davis, K. Maruthi, Q. Yang, M. Woodson, M. A. White, L. M. Miller, M. F. Jarrold, C. E. Catalano, M. Morais

This paper characterizes the biophysical properties and initial structure of λ terminase during DNA translocation, showing a pentameric complex with flexibility and ATP hydrolysis activity.

bioRxiv · Sep 25, 2022 · PreprintBiophysics

Core Protein-Directed Antivirals and Importinβ Can Synergistically Disrupt HBV Capsids

C. Kim, L. F. Barnes, C. J. Schlicksup, A. J. Patterson, B. Bothner, M. F. Jarrold, C.-Y. J. Wang, A. Zlotnick

This study shows that HAP12, a CpAM antiviral, synergizes with importinβ to disrupt HBV capsids, revealing an unexpected mechanism of action involving host protein-induced catalysis.

bioRxiv · Aug 16, 2021 · PreprintMicrobiology

N-terminal VP1 truncations favor T=1 norovirus-like particles

R. Pogan, V. U. Weiss, K. Bond, J. Dülfer, C. Krisp, N. Lyktey, J. Müller-Guhl, S. Zoratto, G. Allmaier, M. F. Jarrold, C. Munoz-Fontela, H. Schlüter, C. Uetrecht

The paper identifies N-terminal VP1 truncations as a cause for T=1 norovirus-like particle formation and discusses implications for vaccine and biotechnological applications.

bioRxiv · Nov 25, 2020Biophysics