M. Feldman

Identification and Characterization of the Lipoprotein N-acyltransferase in Bacteroides

This paper identifies and characterizes Lnb, a lipoprotein N-acyltransferase in Bacteroides, showing its role in lipoprotein biosynthesis and its impact on bacterial growth and polysaccharide degradation.

Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin

This paper shows diclofenac sensitizes colistin-resistant A. baumannii to colistin in vitro and in a mouse model, with reduced drug concentrations needed in vivo.

Dual Membrane-Sspanning Anti-Sigma Factors Regulate Vesiculation in Gut Bacteroidota

This study identifies a novel family of Dual Membrane-spanning Anti-sigma factors (Dma) that regulate Outer Membrane Vesicle (OMV) biogenesis in Bacteroides thetaiotaomicron.

Structure-function conservation between the methyltransferases SETD3 and SETD6

The paper identifies shared and distinct functions of SETD3 and SETD6 in apoptosis regulation through proteomic and RNA-seq analyses of knockout cells.

36-year study reveals stability of a wild wheat population across microhabitats

A 36-year study shows that a wild wheat population's genetic clustering into microhabitats remains stable over time, suggesting local adaptation.

Short-Term Dairy Elimination and Reintroduction Minimally Perturbs the Gut Microbiota in Self-Reported Lactose Intolerant Adults

This study examines the impact of short-term dairy elimination and reintroduction on gut microbiota and lactose tolerance in self-reported lactose intolerant adults, finding minimal microbiota changes and improved symptom tolerance.

Multiplexed detection of SARS-CoV-2 genomic and subgenomic RNA using in situ hybridization

This paper develops an RNA FISH HCR platform to visualize SARS-CoV-2 genomic and subgenomic RNA in autopsy tissues and identifies infected cell types in human lung tissue.

A genetic link between leaf carbon isotope composition and whole-plant water use efficiency in the C4 grass Setaria

This paper identifies genetic loci controlling leaf carbon isotope composition and water use efficiency in C4 grasses, showing their shared genetic basis and potential for marker-assisted breeding.

A dual motif mediates outer-membrane translocation and packing of glycosidases into Bacteroides Outer Membrane Vesicles.

The paper identifies a dual motif in lipoproteins that mediates their translocation and packing into Bacteroides OMVs, supporting their role as public goods.

Evolution Of Hierarchy In Bacterial Metabolic Networks

The paper analyzes bacterial metabolic networks to show flow hierarchy reflects tradeoffs between growth rate and metabolic efficiency, and evolves with ecological strategies.

The Stone Age Plague: 1000 years of Persistence in Eurasia

This study identifies six new Yersinia pestis genomes from the European Late Neolithic to Bronze Age, suggesting a single genetic clade that may have persisted in Europe until the mid Bronze Age.