Author

S. M. Shaffer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

B. L. Emert· 2 shared A. Raj· 1 shared A. Weeraratna· 1 shared C. E. Comar· 1 shared C. H. Danan· 1 shared D. C. Brady· 1 shared D. L. Schaff· 1 shared E. A. McMillan· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

B. L. Emert

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IGF2BP1/IMP1 deletion enhances a facultative stem cell state via regulation of MAP1LC3B

L. R. Parham, P. A. Williams, P. Chatterji, K. Acheampong, C. H. Danan, K. Katada, X. Ma, L. A. Simon, K. E. Naughton, R. Mizuno, T. Karakasheva, E. A. McMillan, K. A. Whelan, D. C. Brady, S. M. Shaffer, K. E. Hamilton

The paper shows that deleting IGF2BP1/IMP1 enhances autophagy and tissue regeneration by regulating MAP1LC3B through phosphorylation and cell stress.

bioRxiv · Feb 28, 2022 · PreprintCell Biology

Multiplexed detection of SARS-CoV-2 genomic and subgenomic RNA using in situ hybridization

K. K. Acheampong, D. L. Schaff, B. L. Emert, J. Lake, S. Reffsin, E. K. Shea, C. E. Comar, L. A. Litzky, N. A. Khurram, R. L. Linn, M. Feldman, S. R. Weiss, K. T. Montone, S. Cherry, S. M. Shaffer

This paper develops an RNA FISH HCR platform to visualize SARS-CoV-2 genomic and subgenomic RNA in autopsy tissues and identifies infected cell types in human lung tissue.

bioRxiv · Aug 11, 2021 · PreprintMicrobiology

Genetic screening for single-cell variability modulators driving therapy resistance

E. A. Torre, E. Arai, S. Bayatpour, L. E. Beck, B. L. Emert, S. M. Shaffer, I. A. Mellis, M. Fane, G. Alicea, K. A. Budinich, A. Weeraratna, J. Shi, A. Raj

This study identifies genes that modulate cellular plasticity and influence therapy resistance in cancer cells through CRISPR screens, showing that manipulating plasticity before therapy can alter resistance.

bioRxiv · Nov 10, 2019Cell Biology