M. Fujioka

A Novel Support Vector Machine-Based One-Day, Single-Dose Prediction Model of Genotoxic Hepatocarcinogenicity in Rats

This paper develops a support vector machine-based model to predict genotoxic hepatocarcinogens in rats using gene expression data from a single dose and day of exposure.

A method for the generation of pseudotyped virus particles bearing SARS coronavirus spike protein in high yields

This paper describes an improved method to produce SARS-CoV and SARS-CoV-2 Spike protein pseudotyped VSV particles for coronavirus entry studies and antiviral development.

Interaction Between Phosphoinositide 3-Kinase and the VDAC2 Channel Tethers Endosomes to Mitochondria and Promotes Endosome Maturation

This study identifies VDAC2 as a mitochondrial protein that binds PI3K, tethers endosomes to mitochondria, and promotes endosome maturation through both structural and pore functions.

Localization of BCR-ABL to stress granules contributes to its oncogenic function

This study shows BCR-ABL localizes to stress granules, and this localization contributes to its oncogenic function in CML.

Folding latency of fluorescent proteins affects the mitochondrial localization of fusion protein

The paper shows that faster folding fluorescent proteins can mislocalize mitochondrial-targeted fusion proteins, and slowing their folding improves mitochondrial localization.