Author

M. Gardel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 5 Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:biophysical modeling· 1 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

J. Devany· 2 shared R. M. Harmon· 2 shared A. Frost· 1 shared A. Murugan· 1 shared A. S. Yap· 1 shared B. Ravaux· 1 shared D. Luvsanjav· 1 shared D. M. Lee· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiophysics

J. Devany

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Limiting Pool and Actin Architecture Controls Myosin Cluster Sizes in Adherent Cells

W.-h. Chou, M. Molaei, H. Wu, P. W. Oakes, J. Beach, M. Gardel

This study measures myosin cluster sizes in adherent cells and finds that cluster growth depends on ROCK activity, myosin self-affinity, and F-actin architecture.

bioRxiv · Jun 7, 2023Biophysics

Tissue confinement regulates cell growth and size in epithelia

J. Devany, M. J. Falk, L. J. Holt, A. Murugan, M. Gardel

This study shows that tissue confinement in epithelia uncouples cell growth from division, leading to reduced cell size and a minimum volume set by genome size.

bioRxiv · Jul 4, 2022 · PreprintBiophysics

Dia1 Coordinates Differentiation and Cell Sorting in a Stratified Epithelium

R. M. Harmon, J. Devany, M. Gardel

This study shows that Dia1, an actin nucleator, drives cell sorting and maintains distinct domains in stratified epithelia by influencing cell density and differentiation.

Journal of Cell Biology · May 2, 2022Peer-reviewedCell Biology

Asymmetric Contraction of Adherens Junctions arises through RhoA and E-cadherin feedback

K. Cavanaugh, M. Staddon, T. A. Chmiel, R. M. Harmon, S. Budnar, A. S. Yap, S. Banerjee, M. Gardel

The paper identifies a feedback loop between RhoA and E-cadherin that drives asymmetric vertex motion in epithelial tissues through tension and frictional drag.

bioRxiv · Feb 26, 2021 · PreprintCell Biology

The mechanisms of dynamin-actin interaction

R. Zhang, N. Gerassimov, D. M. Lee, J. R. Jimah, S. Kim, D. Luvsanjav, J. Winkelman, M. Mettlen, M. E. Abrams, R. Kalia, P. Keene, P. Pandey, B. Ravaux, J. H. Kim, J. A. Ditlev, , E. H. Chen

This study identifies a noncanonical role for dynamin in cell-cell fusion by directly bundling actin filaments through GTPase-dependent interactions.

bioRxiv · Mar 25, 2019 · PreprintCell Biology